Protein Family Models

Sigma-E is important for the induction of proteins involved in heat shock response. RseA binds sigma-E via its N-terminal domain, sequestering sigma-E and preventing transcription from heat-shock promoters [1]. The C-terminal domain is located in the periplasm, and may interact with other protein that signal periplasmic stress. [1]. 9159523. The sigmaE-mediated response to extracytoplasmic stress in Escherichia coli is transduced by RseA and RseB, two negative regulators of sigmaE. De Las Penas A, Connolly L, Gross CA;. Mol Microbiol 1997;24:373-385. (from Pfam)

Date:

2024-10-16

Sigma-E is important for the induction of proteins involved in heat shock response. RseA binds sigma-E via its N-terminal domain, sequestering sigma-E and preventing transcription from heat-shock promoters [1]. The C-terminal domain is located in the periplasm, and may interact with other protein that signal periplasmic stress. [1]. 9159523. The sigmaE-mediated response to extracytoplasmic stress in Escherichia coli is transduced by RseA and RseB, two negative regulators of sigmaE. De Las Penas A, Connolly L, Gross CA;. Mol Microbiol 1997;24:373-385. (from Pfam)

Date:

2024-10-16

anti-sigma-E factor RseA functions as the anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE); ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis

Date:

2019-08-05

Gene:

rseA

Date:

2022-01-26