Protein Family Models

Gene:

rmf

Date:

2024-08-08

This protein associates with 70s ribosomes and converts them to a dimeric form (100S ribosomes) which appear during the transition from the exponential growth phase to the stationary phase of Escherichia coli cells. [1]. 2181444. Structure and probable genetic location of a ribosome modulation factor associated with 100S ribosomes in stationary-phase Escherichia coli cells. Wada A, Yamazaki Y, Fujita N, Ishihama A;. Proc Natl Acad Sci U S A 1990;87:2657-2661. [2]. 8440252. Regulation of the Escherichia coli rmf gene encoding the ribosome modulation factor: growth phase- and growth rate-dependent control. Yamagishi M, Matsushima H, Wada A, Sakagami M, Fujita N, Ishihama A;. EMBO J 1993;12:625-630. (from Pfam)

Date:

2024-10-16

This HMM describes a family of proteins about 60 amino acids in length with a near invariant CPY motif and with highly similar structures as predicted by AlphaFold. Members include Rmf (ribosome modulation factor), the integrative and conjugative element (ICE) protein CrpP, and a putative phage structural protein found encoded major and minor capsid proteins. AlphaFoldDB structures showing similar predicted folds include A0A0Q4SRM6, A0A5B7UVE0, and A0A6L9FUH1.

Date:

2023-07-11

ribosome modulation factor (RMF), during stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes)

Date:

2021-09-30