Protein Family Models

This entry represents the C-terminal domain found in Phosphorylase b kinase regulatory alpha and beta subunits, which control the catalytic activity of the Phosphorylase kinase catalytic gamma subunit. this domain has been proposed as the second calcineurin B-like (CBL-2) domain containing a gamma subunit-binding site [1,2]. [1]. 29098725. The structure of the large regulatory alpha subunit of phosphorylase kinase examined by modeling and hydrogen-deuterium exchange. Rimmer MA, Nadeau OW, Yang J, Artigues A, Zhang Y, Carlson GM;. Protein Sci. 2018;27:472-484. [2]. 18320589. Calcineurin B-like domains in the large regulatory alpha/beta subunits of phosphorylase kinase. Carriere C, Mornon JP, Venien-Bryan C, Boisset N, Callebaut I;. Proteins. 2008;71:1597-1606. (from Pfam)

Date:

2024-10-16

In higher organisms this family is represented by phosphorylase kinase subunits. (from Pfam)

Date:

2024-08-14