Protein Family Models

Kanamycin nucleotidyltransferase (KNTase) is involved in conferring resistance to aminoglycoside antibiotics and catalyses the transfer of a nucleoside monophosphate group from a nucleotide to kanamycin. This enzyme is dimeric with each subunit being composed of two domains. The C-terminal domain contains five alpha helices, four of which are organised into an up-and-down alpha helical bundle. Residues found in this domain may contribute to this enzyme's active site [1]. [1]. 7577914. Structural investigation of the antibiotic and ATP-binding sites. in kanamycin nucleotidyltransferase.. Pedersen LC, Benning MM, Holden HM;. Biochemistry 1995;34:13305-13311. (from Pfam)

Date:

2024-08-14

nucleotidyltransferase domain-containing protein, similar to African swine fever virus repair DNA polymerase X

Date:

2017-03-02

Date:

2021-07-13

Gene:

aadD1

Date:

2021-07-12