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lipid II-degrading bacteriocin
Colicin M is a toxin produced by, and active against, Escherichia coli. It catalyses the hydrolysis of lipid I and lipid II peptidoglycan intermediates, therefore inhibiting peptidoglycan biosynthesis and leading to lysis of the bacterial cells [1]. [1]. 16777846. Colicin M exerts its bacteriolytic effect via enzymatic degradation of undecaprenyl phosphate-linked peptidoglycan precursors. El Ghachi M, Bouhss A, Barreteau H, Touze T, Auger G, Blanot D, Mengin-Lecreulx D;. J Biol Chem. 2006;281:22761-22772. (from Pfam)
Colicin_M domain-containing protein
lipid II-degrading bacteriocin colicin M
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