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DXP reductoisomerase C-terminal domain
This is the C-terminal domain of the 1-deoxy-D-xylulose-5-phosphate reductoisomerase enzyme. This domain forms a left handed super-helix. (from Pfam)
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain
This domain is found to the C-terminus of Pfam:PF02670 domains in bacterial and plant 1-deoxy-D-xylulose 5-phosphate reductoisomerases which catalyse the formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose-5-phosphate in the presence of NADPH [1]. [1]. 9707569. A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the. formation of 2-C-methyl-D-erythritol 4-phosphate in an. alternative nonmevalonate pathway for terpenoid biosynthesis.. Takahashi S, Kuzuyama T, Watanabe H, Seto H;. Proc Natl Acad Sci U S A 1998;95:9879-9884. (from Pfam)
1-deoxy-D-xylulose 5-phosphate reductoisomerase
This is a family of 1-deoxy-D-xylulose 5-phosphate reductoisomerases. This enzyme catalyses the formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose-5-phosphate in the presence of NADPH [1]. This reaction is part of the terpenoid biosynthesis pathway. [1]. 9707569. A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the. formation of 2-C-methyl-D-erythritol 4-phosphate in an. alternative nonmevalonate pathway for terpenoid biosynthesis.. Takahashi S, Kuzuyama T, Watanabe H, Seto H;. Proc Natl Acad Sci U S A 1998;95:9879-9884. (from Pfam)
1-deoxy-D-xylulose-5-phosphate reductoisomerase
1-deoxy-D-xylulose-5-phosphate reductoisomerase catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate
1-deoxy-D-xylulose 5-phosphate is converted to 2-C-methyl-D-erythritol 4-phosphate in the presence of NADPH. It is involved in the synthesis of isopentenyl diphosphate (IPP), a basic building block in isoprenoid, thiamin, and pyridoxal biosynthesis.
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