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PepSY domain-containing protein
This region is likely to have an protease inhibitory function (personal obs:C Yeats). This model is likely to miss some members of this family as the separation from signal to noise is not clear. The name is derived from Peptidase & Bacillus subtilis YPEB. [1]. 7674922. Evolutionary families of metallopeptidases. Rawlings ND, Barrett AJ;. Meth Enzymol 1995;248:183-228. [2]. 15124630. The PepSY domain: a regulator of peptidase activity in the microbial environment?. Yeats C, Rawlings ND, Bateman A;. Trends Biochem Sci 2004;29:169-172. [3]. 15583150. Identification of residues in the Pseudomonas aeruginosa elastase propeptide required for chaperone and secretion activities. McIver KS, Kessler E, Ohman DE;. Microbiology 2004;150:3969-3977. (from Pfam)
PepSY (peptidase propeptide and YPEB) domain-containing protein may act as a regulator of peptidase activity and may also function in protecting the cell from lysis; similar to Bacillus subtilis uncharacterized protein YkoJ and YkoI
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