Protein Family Models

YjbH is a family of Gram-negative beta-barrel outer-membrane lipoproteins that act as putative porins. YbjH is one of four gene-products expressed from an operon, yjbEFGH, which is regulated by the Rcs phosphorelay in a RcsA-dependent manner, similar to that of other exopolysaccharide biosynthetic pathways. It is highly possible that the yjbEFGH operon encodes a system involved in EPS secretion since none of the products is predicted to have enzymic activity, the products are all secreted and YbjH and F are predicted to be beta-barrel lipoproteins similar to porins. It may be that the operon products play some role in biofilm formation and/or matrix production [1]. [1]. 17379715. The yjbEFGH locus in Escherichia coli K-12 is an operon encoding proteins involved in exopolysaccharide production. Ferrieres L, Aslam SN, Cooper RM, Clarke DJ;. Microbiology. 2007;153:1070-1080. [2]. 21449614. Crystal structure of E. coli group 4 capsule protein GfcC reveals a domain organization resembling Wza. Sathiyamoorthy K, Mills E, Franzmann TM, Rosenshine I, Saper MA;. Biochemistry 2011;0:0-0. (from Pfam)

Date:

2024-10-16

YjbH domain-containing protein, similar to Escherichia coli K-12 YjbH which is a putative lipoprotein and/or porin involved in exopolysaccharide production

Date:

2016-11-08