Protein Family Models for Protein (Select 446662227) - Protein Family Models

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Items: 4

Select item 4261561.

Formyl peptide receptor-like 1 inhibitory protein

This family consists of several formyl peptide receptor-like 1 inhibitory proteins from Staphylococcus aureus. These are secreted proteins that block the formyl peptide receptor-like 1 found in neutrophils, monocytes, B cells, and NK cells; and inhibit the binding of chemoattractants (such as formylated peptides) to FPRL1, which initiate phagocyte mobilization towards the infection site [1]. [1]. 17114475. A new staphylococcal anti-inflammatory protein that antagonizes the formyl peptide receptor-like 1. Prat C, Bestebroer J, de Haas CJ, van Strijp JA, van Kessel KP;. J Immunol. 2006 Dec 1;177(11):8017-26. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF027430.5
Method:: HMM

Select item 4030492.

new record, indexing in progress

Family Accession:

Select item 3588303.

new record, indexing in progress

Family Accession:

Select item 1853414.

FPRL1 inhibitory protein FLIPr

FPRL1 inhibitory protein (FLIPr); secreted protein that blocks the formyl peptide receptor-like 1 (FPRL1) found in neutrophils, monocytes, B cells, and NK cells; inhibits the binding of chemoattractants (such as formylated peptides) to FPRL1, which initiates the phagocyte mobilization towards the infection site. Some authors refer to the branch of the family that includes WP_000739558.1 as FLIPr-like rather than FLIPr, but it appears that no Staphylococcus aureus genome encodes both FLIPr and FLIPr-like.