Protein Family Models for Protein (Select 446633678) - Protein Family Models

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Items: 4

Select item 2345801.

PRK15363 family protein

Date:: 2017-03-02

Family Accession:: 11487753
Method:: Sparcle

Select item 1982772.

SycD/LcrH family type III secretion system chaperone SscA

Gene:: sscA

Date:: 2020-03-04

Family Accession:: NBR011397
Method:: BlastRule

Select item 1594423.

CesD/SycD/LcrH family type III secretion system chaperone SscA

Gene:: sscA

Date:: 2020-10-26

Family Accession:: NF011890.0
Method:: HMM

Select item 509554.

SycD/LcrH family type III secretion system chaperone

Genes in this family are found in type III secretion operons. LcrH, from Yersinia is believed to have a regulatory function in the low-calcium response of the secretion system [1,2]. The same protein is also known as SycD (SYC = Specific Yop Chaperone) for its chaperone role [3]. In Pseudomonas, where the homolog is known as PcrH, the chaperone role has been demonstrated and the regulatory role appears to be absent [4]. ScyD/LcrH contains three central tetratricopeptide-like repeats that are predicted to fold into an all-alpha-helical array [5].