Protein Family Models for Protein (Select 446480312) - Protein Family Models

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Items: 4

Select item 4203321.

type II toxin-antitoxin system HigB family toxin

HigB_toxin is a family of RelE-like prokaryotic proteins that function as mRNA interferases. HigB cleaves translated mRNA only, and cleavage depended on translation of the target RNAs. HigB belongs to the RelE super-family of RNases. The toxin-antitoxin gene-pair is induced by environmental stress factors. [1]. 19943910. Three new RelE-homologous mRNA interferases of Escherichia coli differentially induced by environmental stresses. Christensen-Dalsgaard M, Jorgensen MG, Gerdes K;. Mol Microbiol. 2010;75:333-348. (from Pfam)

GO Terms:

Molecular Function:: RNA binding (GO:0003723)

Molecular Function:: endonuclease activity (GO:0004519)

Biological Process:: nucleic acid metabolic process (GO:0090304)

Cellular Component:: toxin-antitoxin complex (GO:0110001)

Date:: 2024-10-16

Family Accession:: NF021431.5
Method:: HMM

Select item 3981272.

new record, indexing in progress

Family Accession:

Select item 3597273.

new record, indexing in progress

Family Accession:

Select item 2113324.

type II toxin-antitoxin system HigB family toxin

type II toxin-antitoxin (TA) system HigB family toxin similar to Escherichia coli mRNA interferase HigB, the toxin component of the HigB-HigA TA system; induced by amino acid starvation