Protein Family Models for Protein (Select 446389163) - Protein Family Models

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Links from Protein

Items: 7

Select item 4143631.

C4-dicarboxylate anaerobic carrier

GO Terms:

Cellular Component:: membrane (GO:0016020)

Date:: 2024-08-14

Family Accession:: NF015563.5
Method:: HMM

Select item 3897242.

new record, indexing in progress

Family Accession:

Select item 3500113.

new record, indexing in progress

Family Accession:

Select item 548294.

PRK09804 family protein

Date:: 2017-03-02

Family Accession:: 10013345
Method:: Sparcle

Select item 221385.

C4-dicarboxylate anaerobic carrier, DcuC family

These proteins are members of the C4-dicarboxylate Uptake C (DcuC) Family (TC 2.A.61). The only functionally characterized member of this family is the anaerobic C4-dicarboxylate transporter (DcuC) of Escherichia coli. DcuC has 12 GES predicted transmembrane regions, is induced only under anaerobic conditions, and is not repressed by glucose. It may therefore function as a succinate efflux system during anaerobic glucose fermentation. However, when overexpressed, it can replace either DcuA or DcuB, which are unrelated, in catalyzing fumarate-succinate exchange and fumarate uptake.

GO Terms:

Cellular Component:: plasma membrane (GO:0005886)

Molecular Function:: C4-dicarboxylate transmembrane transporter activity (GO:0015556)

Biological Process:: C4-dicarboxylate transport (GO:0015740)

Date:: 2023-11-14

Family Accession:: TIGR00771.1
Method:: HMM

Select item 208866.

C4-dicarboxylate transporter DcuC

Proteins of this family usually have 11-12 transmembrane regions. They transport C4-dicarboxylates under anaerobic conditions, which plays an important role in anaerobic energy metabolism.