Protein Family Models

This domain is found in conserved virulence factors [1]. It is often found in association with Pfam:PF02985 and Pfam:PF08712. [1]. 15853881. Silkworm pathogenic bacteria infection model for identification of novel virulence genes. Kaito C, Kurokawa K, Matsumoto Y, Terao Y, Kawabata S, Hamada S, Sekimizu K;. Mol Microbiol. 2005;56:934-944. (from Pfam)

Date:

2024-10-16

This family includes multiple HEAT repeats. (from Pfam)

Date:

2024-08-14

This domain is found at the N terminus of NifU and NifU related proteins, and in the human Nfu protein. Both of these proteins are thought to be involved in the the assembly of iron-sulphur clusters [1][2]. [1]. 12886008. Subcellular compartmentalization of human Nfu, an iron-sulfur cluster scaffold protein, and its ability to assemble a [4Fe-4S] cluster. Tong WH, Jameson GN, Huynh BH, Rouault TA;. Proc Natl Acad Sci U S A. 2003;100:9762-9767. [2]. 14993221. Iron-sulfur cluster assembly: NifU-directed activation of the nitrogenase Fe protein. Dos Santos PC, Smith AD, Frazzon J, Cash VL, Johnson MK, Dean DR;. J Biol Chem. 2004;279:19705-19711. (from Pfam)

Date:

2024-10-16

The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see Pfam:PF00514). [1]. 7550332. HEAT repeats in the Huntington's disease protein. Andrade MA, Bork P;. Nat Genet 1995;11:115-116. [2]. 9989501. The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs. Groves MR, Hanlon N, Turowski P, Hemmings BA, Barford D;. Cell 1999;96:99-110. (from Pfam)

Date:

2024-10-16

protein similar to conserved virulence factor C

Date:

2017-03-02