Protein Family Models for Protein (Select 446270448) - Protein Family Models

Warning: The NCBI web site requires JavaScript to function. more...

Format

Summary
Summary (text)
UI List

Sort by

Default order
Publication Date (up)
Publication Date (down)

Send to:

Choose Destination

File
Clipboard
Collections

Links from Protein

Items: 5

Select item 4124771.

DNA-3-methyladenine glycosylase

Methylpurine-DNA glycosylase is a base excision-repair protein. It is responsible for the hydrolysis of the deoxyribose N-glycosidic bond, excising 3-methyladenine and 3-methylguanine from damaged DNA. [1]. 9790531. Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision. Lau AY, Scharer OD, Samson L, Verdine GL, Ellenberger T;. Cell 1998;95:249-258. (from Pfam)

GO Terms:

Molecular Function:: DNA binding (GO:0003677)

Molecular Function:: alkylbase DNA N-glycosylase activity (GO:0003905)

Biological Process:: base-excision repair (GO:0006284)

Date:: 2024-10-16

Family Accession:: NF014316.5
Method:: HMM

Select item 3897392.

new record, indexing in progress

Family Accession:

Select item 3475413.

new record, indexing in progress

Family Accession:

Select item 2532824.

DNA-3-methyladenine glycosylase

DNA-3-methyladenine glycosylase is responsible for recognizing base lesions in the genome and initiating base excision DNA repair

Date:: 2017-03-24

Family Accession:: 10087981
Method:: Sparcle

Select item 218525.

DNA-3-methyladenine glycosylase

This families are based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). All proteins in this family for which the function is known are involved in the base excision repair of alkylation damage to DNA. The exact specificty of the type of alkylation damage repaired by each of these varies somewhat between species. Substrates include 3-methyl adenine, 7-methyl-guanaine, and 3-methyl-guanine.

GO Terms: