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L-rhamnose isomerase
This family consists of several bacterial L-rhamnose isomerase proteins (EC:5.3.1.14). [1]. 10891278. The structure of rhamnose isomerase from Escherichia coli and its relation with xylose isomerase illustrates a change between inter and intra-subunit complementation during evolution. Korndorfer IP, Fessner WD, Matthews BW;. J Mol Biol 2000;300:917-933. (from Pfam)
L-rhamnose isomerase catalyzes the formation of L-rhamnulose from L-rhamnose
Catalyzes the formation of L-rhamnulose from L-rhamnose
This enzyme interconverts L-rhamnose and L-rhamnulose. In some species, including E. coli, this is the first step in rhamnose catabolism. Sequential steps are catalyzed by rhamnulose kinase (rhaB), then rhamnulose-1-phosphate aldolase (rhaD) to yield glycerone phosphate and (S)-lactaldehyde. Characterization of this family is based on members in E. coli and Salmonella.
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