Protein Family Models

This entry represents a domain found in the YozE-like family. YozE-like is a family of Firmicute proteins that carries a four-helix motif similar to sterile alpha motif (SAM) domains. The family is suggested to fall into two subfamilies, possibly with differing functions based on the different surface charges on the three structural representatives, YozE MW0776 and MW1311. What this function is is not yet known although it is likely to involve binding to DNA [1]. [1]. 22843344. Three structural representatives of the PF06855 protein domain family from Staphyloccocus aureus and Bacillus subtilis have SAM domain-like folds and different functions. Swapna GV, Rossi P, Montelione AF, Benach J, Yu B, Abashidze M, Seetharaman J, Xiao R, Acton TB, Tong L, Montelione GT;. J Struct Funct Genomics. 2012;13:163-170. (from Pfam)

Date:

2024-10-16

sterile alpha motif-like domain-containing protein adopts a four-helix motif, similar to MW0776 and MW1311 from Staphyloccocus aureus and yozE from Bacillus subtilis

Date:

2020-06-26