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thiamine pyrophosphate-dependent enzyme
thiamine pyrophosphate-binding protein
Thiamine pyrophosphate enzyme, central domain
The central domain of TPP enzymes contains a 2-fold Rossman fold. [1]. 8604141. Crystal structure of the thiamin diphosphate-dependent enzyme. pyruvate decarboxylase from the yeast Saccharomyces cerevisiae. at 2.3 A resolution.. Arjunan P, Umland T, Dyda F, Swaminathan S, Furey W, Sax M,. Farrenkopf B, Gao Y, Zhang D, Jordan F;. J Mol Biol 1996;256:590-600. (from Pfam)
oxalyl-CoA decarboxylase
In a number of bacteria, including Oxalobacter formigenes from the human gut, a two-gene operon of oxc (oxalyl-CoA decarboxylase) and frc (formyl-CoA transferase) encodes a system for degrading and therefore detoxifying oxalate. Members of this family are the thiamine pyrophosphate (TPP)-containing enzyme oxalyl-CoA decarboxylase.
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