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Glycine cleavage system P-protein
This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1.2.10 (GDC) also annotated as glycine cleavage system or glycine synthase. GDC consists of four proteins P, H, L and T [2]. The reaction catalysed by this protein is:- Glycine + lipoylprotein <=> S-aminomethyldihydrolipoylprotein + CO2 [1]. 7498764. Genetics of the synthesis of serine from glycine and the utilization of glycine as sole nitrogen source by Saccharomyces cerevisiae. Sinclair DA, Dawes IW;. Genetics 1995;140:1213-1222. [2]. 8181752. Characterization of the Escherichia coli gcv operon. Stauffer LT, Fogarty SJ, Stauffer GV;. Gene 1994;142:17-22. (from Pfam)
aminomethyl-transferring glycine dehydrogenase subunit GcvPA
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