Protein Family Models for Protein (Select 2732734169) - Protein Family Models

Select item 4275221.

A SWi2/SNF2 ATPase found in polyvalent proteins [1]. [1]. 28559295. Polyvalent Proteins, a Pervasive Theme in the Intergenomic Biological Conflicts of Bacteriophages and Conjugative Elements. Iyer LM, Burroughs AM, Anand S, de Souza RF, Aravind L;. J Bacteriol. 2017; [Epub ahead of print] (from Pfam)

Date:: 2024-10-16

Family Accession:: NF037510.5
Method:: HMM

Select item 4272602.

DUF4145 domain-containing protein

This domain is found in a variety of restriction endonuclease enzymes. The exact function of this domain is uncertain. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF025027.5
Method:: HMM

Select item 4187763.

type I restriction-modification enzyme R subunit C-terminal domain-containing protein

The restriction enzyme EcoEI recognises 5'-GAGN(7)ATGC-3' and is composed of the three proteins R, M, and S. The domain described here is found at the C-terminus of the R protein (HsdR) which is required for both nuclease and ATPase activity [1,2]. [1]. 8412658. Conservation of motifs within the unusually variable polypeptide sequences of type I restriction and modification enzymes. Murray NE, Daniel AS, Cowan GM, Sharp PM;. Mol Microbiol 1993;9:133-143. [2]. 10449767. Regulation of endonuclease activity by proteolysis prevents breakage of unmodified bacterial chromosomes by type I restriction enzymes. Makovets S, Doronina VA, Murray NE;. Proc Natl Acad Sci U S A 1999;96:9757-9762. (from Pfam)

GO Terms:

Molecular Function:: DNA binding (GO:0003677)

Molecular Function:: catalytic activity (GO:0003824)

Biological Process:: DNA modification (GO:0006304)

Date:: 2024-10-16

Family Accession:: NF020052.5
Method:: HMM

Select item 4149164.

DEAD/DEAH box helicase family protein

GO Terms:

Molecular Function:: DNA binding (GO:0003677)

Molecular Function:: ATP binding (GO:0005524)

Molecular Function:: hydrolase activity (GO:0016787)

Date:: 2024-08-14

Family Accession:: NF016724.5
Method:: HMM

Select item 4118845.

DEAD/DEAH box helicase

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression. [1]. 10322435. Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. de la Cruz J, Kressler D, Linder P;. Trends Biochem Sci 1999;24:192-198. [2]. 9862990. The DEAD box RNA helicase family in Arabidopsis thaliana. Aubourg S, Kreis M, Lecharny A;. Nucleic Acids Res 1999;27:628-636. (from Pfam)

GO Terms:

Molecular Function:: nucleic acid binding (GO:0003676)

Molecular Function:: ATP binding (GO:0005524)

Date:: 2024-10-16

Family Accession:: NF012492.5
Method:: HMM

Select item 4117616.

helicase-related protein

The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF012493.5
Method:: HMM

Select item 4088397.