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GLUG motif-containing protein
This family is found in the IgA1 (M26) peptidases, which attached to the cell wall peptidoglycan by an amide bond ([1]). IgA1 protease selectively cleaves human IgA1 and is likely to be a pathogenicity factor in some pathogens ([2]). This family is also found in various other contexts, including with Pfam:PF05860. It is named GLUG after the mostly conserved G-L-any-G motif. [1]. 8926055. Characterization of the Streptococcus pneumoniae immunoglobulin. A1 protease gene (iga) and its translation product.. Poulsen K, Reinholdt J, Kilian M;. Infect Immun 1996;64:3957-3966.. [2]. 12841855. The three extra-cellular zinc metalloproteinases of. Streptococcus pneumoniae have a different impact on virulence in. mice.. Chiavolini D, Memmi G, Maggi T, Iannelli F, Pozzi G, Oggioni MR;. BMC Microbiol 2003;3:14. (from Pfam)
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