Protein Family Models for Protein (Select 2700315659) - Protein Family Models

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Items: 3

Select item 4117251.

exonuclease domain-containing protein

This family includes a variety of exonuclease proteins, such as ribonuclease T and the epsilon subunit of DNA polymerase III.; [1]. 8506149. RNase T shares conserved sequence motifs with DNA proofreading exonucleases. Koonin EV, Deutscher MP;. Nucleic Acids Res 1993;21:2521-2522. (from Pfam)

GO Terms:

Molecular Function:: exonuclease activity (GO:0004527)

Date:: 2024-10-16

Family Accession:: NF013122.5
Method:: HMM

Select item 3883482.

new record, indexing in progress

Family Accession:

Select item 223773.

exonuclease, DNA polymerase III, epsilon subunit family

All proteins in this family for which functions are known are components of the DNA polymerase III complex (epsilon subunit). There is, however, an outgroup that includes paralogs in some gamma-proteobacteria and the n-terminal region of DinG from some low GC gram positive bacteria. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).

GO Terms: