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PDZ domain-containing protein
This entry represents the PDZ domain from a wide variety of proteins. (from Pfam)
trypsin-like peptidase domain-containing protein
This family includes trypsin-like peptidase domains. (from Pfam)
trypsin-like serine protease
PDZ domains are found in diverse signaling proteins. Review article. [1]. 9204764. PDZ domains: targeting signalling molecules to sub-membranous sites. Ponting CP, Phillips C, Davies KE, Blake DJ. Bioessays 1997;19:469-479. [2]. 8674113. Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ. Doyle DA, Lee A, Lewis J, Kim E, Sheng M, MacKinnon R;. Cell. 1996;85:1067-1076. Extension of PDZ family. [3]. 9041651. Evidence for PDZ domains in bacteria, yeast, and plants. Ponting CP;. Protein Sci 1997;6:464-468. [4]. 19738200. Rapid evolution of functional complexity in a domain family. Ernst A, Sazinsky SL, Hui S, Currell B, Dharsee M, Seshagiri S, Bader GD, Sidhu SS;. Sci Signal. 2009;2:ra50. (from Pfam)
S1C family serine protease
S1C family serine protease containing a C-terminal PDZ domain, similar to the Deg/high-temperature requirement factor A (HtrA) family of housekeeping serine proteases that participate in folding and degradation of aberrant proteins, and in processing and maturation of native proteins
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