Protein Family Models

This domain is found at the C-terminal end of the group of bacterial glycosyl hydrolases 109, including Alpha-N-acetylgalactosaminidase from Elizabethkingia meningoseptica. This domain shows a large open-faced, seven-stranded, anti-parallel beta-sheet, adjacent to nine alpha-helices and an alpha-helical bundle covering the dinucleotide-binding tunnel [1]. Paper describing PDB structure 2ixa. [1]. 17401360. Bacterial glycosidases for the production of universal red blood cells. Liu QP, Sulzenbacher G, Yuan H, Bennett EP, Pietz G, Saunders K, Spence J, Nudelman E, Levery SB, White T, Neveu JM, Lane WS, Bourne Y, Olsson ML, Henrissat B, Clausen H;. Nat Biotechnol. 2007;25:454-464. (from Pfam)

Date:

2024-10-16

This family of enzymes utilise NADP or NAD. This family is called the GFO/IDH/MOCA family in swiss-prot. [1]. 8994968. The structure of glucose-fructose oxidoreductase from Zymomonas mobilis: an osmoprotective periplasmic enzyme containing non-dissociable NADP. Kingston RL, Scopes RK, Baker EN;. Structure 1996;4:1413-1428. (from Pfam)

Date:

2024-10-16

Gfo/Idh/MocA family protein belonging to the NAD(P)(+)-binding Rossmann-fold superfamily, may function as an oxidoreductase that catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

Date:

2024-05-20