Protein Family Models

Date:

2024-08-14

This is a leucine-zipper-like or homeodomain-like region of transposase TnpC of insertion element IS66. [1]. 11418571. Structural and functional characterization of IS679 and IS66-family elements. Han CG, Shiga Y, Tobe T, Sasakawa C, Ohtsubo E;. J Bacteriol 2001;183:4296-4304. (from Pfam)

Date:

2024-10-16

This is a zinc-finger region of the N-terminus of the insertion element IS66 transposase. [1]. 11418571. Structural and functional characterization of IS679 and IS66-family elements. Han CG, Shiga Y, Tobe T, Sasakawa C, Ohtsubo E;. J Bacteriol 2001;183:4296-4304. (from Pfam)

Date:

2024-10-16

Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens [2]. [1]. 8167368. An open reading frame downstream of Rhizobium meliloti nodQ1 shows nucleotide sequence similarity to an Agrobacterium tumefaciens insertion sequence. Schwedock J, Long SR;. Mol Plant Microbe Interact 1994;7:151-153. Naming of IS66. [2]. 6095299. Nucleotide sequence of the insertion sequence found in the T-DNA region of mutant Ti plasmid pTiA66 and distribution of its homologues in octopine Ti plasmid. Machida Y, Sakurai M, Kiyokawa S, Ubasawa A, Suzuki Y, Ikeda JE;. Proc Natl Acad Sci USA 1984;81:7495-7499. (from Pfam)

Date:

2024-10-16

IS66 family transposase binds to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Date:

2024-12-16

Members of this protein family are DDE transposases from the IS66 family insertion sequences, which typically consist of two accessary genes (TnpA and TnpB) and the third gene encoding the transposase.

Gene:

tnpC

Date:

2024-09-30

Date:

2019-09-10

Date:

2019-09-10

Date:

2019-09-10