This entry represents the N-terminal domain from 4'- phosphopantetheinyl transferase enzymes. This domain is structurally related to the Pfam:PF01648 domain with which it forms a pseudodimeric arrangement [2]. [1]. 10997907. Crystal structures of substrate binding to Bacillus subtilis. holo-(acyl carrier protein) synthase reveal a novel trimeric. arrangement of molecules resulting in three active sites.. Parris KD, Lin L, Tam A, Mathew R, Hixon J, Stahl M, Fritz CC,. Seehra J, Somers WS;. Structure. 2000;8:883-895.. [2]. 24963544. Structure, biochemistry, and inhibition of essential. 4'-phosphopantetheinyl transferases from two species of. Mycobacteria.. Vickery CR, Kosa NM, Casavant EP, Duan S, Noel JP, Burkart MD;. ACS Chem Biol. 2014;9:1939-1944.. [3]. 22993090. Structural characterization and comparison of three. acyl-carrier-protein synthases from pathogenic bacteria.. Halavaty AS, Kim Y, Minasov G, Shuvalova L, Dubrovska I, Winsor. J, Zhou M, Onopriyenko O, Skarina T, Papazisi L, Kwon K,. Peterson SN, Joachimiak A, Savchenko A, Anderson WF;. Acta Crystallogr D Biol Crystallogr. 2012;68:1359-1370. (from Pfam)
- Date:
- 2024-08-14