Protein Family Models for Protein (Select 2279645252) - Protein Family Models

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Items: 7

Select item 4161911.

NEAT domains are heme and/or hemoprotein-binding modules highly conserved in secondary structure [1]. They have roles in hemoprotein binding, heme extraction and heme transfer [2] [1]. 25153520. Molecular and evolutionary analysis of NEAr-iron Transporter (NEAT) domains. Honsa ES, Maresso AW, Highlander SK;. PLoS One. 2014;9:e104794. [2]. 25862688. Recent developments in understanding the iron acquisition strategies of gram positive pathogens. Sheldon JR, Heinrichs DE;. FEMS Microbiol Rev. 2015;39:592-630. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF016890.5
Method:: HMM

Select item 4124892.

LPXTG cell wall anchor motif

Date:: 2024-08-14

Family Accession:: NF012948.5
Method:: HMM

Select item 3923673.

new record, indexing in progress

Family Accession:

Select item 3892884.

new record, indexing in progress

Family Accession:

Select item 3502025.

new record, indexing in progress

Family Accession:

Select item 3467136.

new record, indexing in progress

Family Accession:

Select item 1409167.

LPXTG cell wall anchor domain-containing protein

This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region.

GO Terms: