Protein Family Models

This family consists of a group of bacteriophage replication gene A protein (GPA) like sequences from both viruses and bacteria. The members of this family are likely to be endonucleases [1,2,3]. [1]. 8510152. Studies of bacteriophage P2 DNA replication. The DNA sequence of the cis-acting gene A and ori region and construction of a P2 mini-chromosome. Liu Y, Saha S, Haggard-Ljungquist E;. J Mol Biol 1993;231:361-374. [2]. 7997180. Identification of an HP1 phage protein required for site-specific excision. Esposito D, Scocca JJ;. Mol Microbiol 1994;13:685-695. [3]. 1701261. Retron for the 67-base multicopy single-stranded DNA from Escherichia coli: a potential transposable element encoding both reverse transcriptase and Dam methylase functions. Hsu MY, Inouye M, Inouye S;. Proc Natl Acad Sci U S A 1990;87:9454-9458. [4]. 158588. Role of polymeric forms of the bacteriophage phi X174 coded gene A protein in phi XRFI DNA cleavage. Ikeda JE, Yudelevich A, Shimamoto N, Hurwitz J;. J Biol Chem 1979;254:9416-9428. [5]. 2940511. Two juxtaposed tyrosyl-OH groups participate in phi X174 gene A protein catalysed cleavage and ligation of DNA. van Mansfeld AD, van Teeffelen HA, Baas PD, Jansz HS;. Nucleic Acids Res 1986;14:4229-4238. (from Pfam)

Date:

2024-10-16