Protein Family Models

Some members of this family have been annotated as helicases. [1]. 8645296. A new plasmid-encoded proteic killer gene system: cloning, sequencing, and analyzing hig locus of plasmid Rts1. Tian QB, Ohnishi M, Tabuchi A, Terawaki Y;. Biochem Biophys Res Commun 1996;220:280-284. [2]. 8078071. Molecular cloning and expression of a novel hydroxymethylcytosine-specific restriction enzyme (PvuRts1I) modulated by glucosylation of DNA. Janosi L, Yonemitsu H, Hong H, Kaji A;. J Mol Biol 1994;242:45-61. [3]. 12426355. Gene islands integrated into tRNA(Gly) genes confer genome diversity on a Pseudomonas aeruginosa clone. Larbig KD, Christmann A, Johann A, Klockgether J, Hartsch T, Merkl R, Wiehlmann L, Fritz HJ, Tummler B;. J Bacteriol 2002;184:6665-6680. [4]. 12107144. Genomic and functional analyses of SXT, an integrating antibiotic resistance gene transfer element derived from Vibrio cholerae. Beaber JW, Hochhut B, Waldor MK;. J Bacteriol 2002;184:4259-4269. [5]. 14506243. Extent of Single-stranded DNA Required for Efficient TraI Helicase Activity in Vitro. Csitkovits VC, Zechner EL;. J Biol Chem 2003;278:48696-48703. [6]. 12637015. Subdomain organization and catalytic residues of the F factor TraI relaxase domain. Street LM, Harley MJ, Stern JC, Larkin C, Williams SL, Miller DL, Dohm JA, Rodgers ME, Schildbach JF;. Biochim Biophys Acta 2003;1646:86-99. (from Pfam)

Date:

2024-10-16

Date:

2024-08-14

Members of this protein family are the TraI putative relaxases required for transfer by a subclass of integrating conjugative elements (ICE) as found in Pseudomonas fluorescens Pf-5, and understood from study of two related ICE, SXT and R391. This model represents the N-terminal domain. Note that no homology is detected to the similarly named TraI relaxase of the F plasmid.

Gene:

traI

Date:

2019-09-10