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Links from Protein

Items: 6

1.

TolC family protein

The OEP family (Outer membrane efflux protein) form trimeric channels that allow export of a variety of substrates in Gram negative bacteria. Each member of this family is composed of two repeats. The trimeric channel is composed of a 12 stranded all beta sheet barrel that spans the outer membrane, and a long all helical barrel that spans the periplasm. [1]. 10092468. Alignment and structure prediction of divergent protein families: periplasmic and outer membrane proteins of bacterial efflux pumps. Johnson JM, Church GM;. J Mol Biol 1999;287:695-715. (from Pfam)

GO Terms:
Molecular Function:
efflux transmembrane transporter activity (GO:0015562)
Biological Process:
transmembrane transport (GO:0055085)
Date:
2024-10-16
Family Accession:
NF014385.5
Method:
HMM
2.
new record, indexing in progress
Family Accession:
3.
new record, indexing in progress
Family Accession:
4.

efflux transporter outer membrane subunit

efflux transporter outer membrane subunit similar to Escherichia coli cation efflux system protein CusC and Salmonella enterica outer membrane lipoprotein SilC

Date:
2019-08-09
Family Accession:
11484501
Method:
Sparcle
5.

efflux transporter outer membrane subunit

Members of this HMM comprise a subfamily of the Outer Membrane Factor (TCDB 1.B.17) porins. OMF proteins operate in conjunction with a primary transporter of the RND, MFS, ABC, or PET systems, and a MFP (membrane fusion protein) to tranport substrates across membranes. The complex thus formed allows transport (export) of various solutes (heavy metal cations; drugs, oligosaccharides, proteins, etc.) across the two envelopes of the Gram-negative bacterial cell envelope in a single energy-coupled step. Current data suggest that the OMF (and not the MFP) is largely responsible for the formation of both the trans-outer membrane and trans-periplasmic channels. The roles played by the MFP have yet to be determined.

GO Terms:
Biological Process:
transport (GO:0006810)
Cellular Component:
cell outer membrane (GO:0009279)
Molecular Function:
porin activity (GO:0015288)
Date:
2021-04-27
Family Accession:
TIGR01845.1
Method:
HMM
6.

Cu(I)/Ag(I) efflux RND transporter outer membrane protein

Part of a cation efflux system that mediates resistance to copper and silver

Date:
2020-10-26
Family Accession:
NF007347.1
Method:
HMM
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