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Glutamate-cysteine ligase
Family of bacterial f glutamate-cysteine ligases (EC:6.3.2.2) that carry out the first step of the glutathione biosynthesis pathway. (from Pfam)
glutamate--cysteine ligase
glutamate--cysteine ligase catalyzes the conversion of ATP, L-glutamate, and L-cysteine to ADP, phosphate, and gamma-L-glutamyl-L-cysteine
Alternate name: gamma-glutamylcysteine synthetase. This HMM represents glutamate--cysteine ligase, and enzyme in the biosynthesis of glutathione (GSH). GSH is one of several low molecular weight cysteine derivatives that can serve to protect against oxidative damage and participate in a biosynthetic or detoxification reactions.
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