Protein Family Models

This family of proteins is functionally uncharacterised. This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 292 and 338 amino acids in length. (from Pfam)

Date:

2024-08-14

The WecG member of this family, believed to be UDP-N-acetyl-D-mannosaminuronic acid transferase, plays a role in enterobacterial common antigen (eca) synthesis in Escherichia coli. Another family member, the Bacillus subtilis TagA protein, is involved in the biosynthesis of the cell wall polymer poly(glycerol phosphate). The third family member, CpsF, CMP-N-acetylneuraminic acid synthetase has a role in the capsular polysaccharide biosynthesis pathway. Also included in this group is Xanthomonas campestris pv. campestris GumM, a glycosyltransferase participating in the biosynthesis of the exopolysaccharide xanthan [1, 2, 3, 4, 5, 6, 7]. [1]. 8830246. Characterization of cpsF and its product CMP-N-acetylneuraminic acid synthetase, a group B streptococcal enzyme that can function in K1 capsular polysaccharide biosynthesis in Escherichia coli. Haft RF, Wessels MR, Mebane MF, Conaty N, Rubens CE;. Mol Microbiol. 1996;19:555-563. [2]. 11673418. Identification of the structural gene for the TDP-Fuc4NAc:lipid II Fuc4NAc transferase involved in synthesis of enterobacterial common antigen in Escherichia coli K-12. Rahman A, Barr K, Rick PD;. J Bacteriol 2001;183:6509-6516. [3]. 12618464. Identification and biosynthesis of cyclic enterobacterial common antigen in Escherichia coli. Erbel PJ, Barr K, Gao N, Gerwig GJ, Rick PD, Gardner KH;. J Bacteriol. 2003;185:1995-2004. [4]. 18156271. Localization and interactions of teichoic acid synthetic enzymes in Bacillus subtilis. Formstone A, Carballido-Lopez R, Noirot P, Errington J, Scheffers DJ;. J Bacteriol. 2008;190:1812-1821. [5]. 16953575. Acceptor substrate selectivity and kinetic mec. TRUNCATED at 1650 bytes (from Pfam)

Date:

2024-10-16

WecB/TagA/CpsF family glycosyltransferase catalyzes the formation of glycosidic bonds and may be involved in the biosynthesis of repeating polysaccharide units found in membrane glycolipids

Date:

2019-02-14

The WecG member of this superfamily, believed to be UDP-N-acetyl-D-mannosaminuronic acid transferase, plays a role in enterobacterial common antigen (eca) synthesis in Escherichia coli. Another family member, the Bacillus subtilis TagA protein, is involved in the biosynthesis of the cell wall polymer poly(glycerol phosphate). The third family member, CpsF, CMP-N-acetylneuraminic acid synthetase has a role in the capsular polysaccharide biosynthesis pathway.

Date:

2021-04-27