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helix-turn-helix domain-containing protein
This DNA-binding motif is found in four copies in the pipsqueak protein of Drosophila melanogaster [1]. In pipsqueak this domain binds to GAGA sequence [1]. [1]. 9774480. The pipsqueak protein of Drosophila melanogaster binds to GAGA sequences through a novel DNA-binding domain. Lehmann M, Siegmund T, Lintermann KG, Korge G;. J Biol Chem 1998;273:28504-28509. [2]. 11976954. The Drosophila Pipsqueak protein defines a new family of helix-turn-helix DNA-binding proteins. Siegmund T, Lehmann M;. Dev Genes Evol 2002;212:152-157. [3]. 11731471. The Drosophila ribbon gene encodes a nuclear BTB domain protein that promotes epithelial migration and morphogenesis. Shim K, Blake KJ, Jack J, Krasnow MA;. Development 2001;128:4923-4933. (from Pfam)
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