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WxcM-like domain-containing protein
This family includes FdtA (Swiss:Q6T1W8) from Aneurinibacillus thermoaerophilus, which has been characterised as a dtdp-6-deoxy-3,4-keto-hexulose isomerase [1]. It also includes WxcM (Swiss:Q93S92) from Xanthomonas campestris (pv. campestris) [2]. [1]. 12740380. Biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose in Aneurinibacillus thermoaerophilus L420-91T. Pfoestl A, Hofinger A, Kosma P, Messner P;. J Biol Chem 2003;278:26410-26417. [2]. 11589581. Lipopolysaccharide biosynthesis in Xanthomonas campestris pv. campestris: a cluster of 15 genes is involved in the biosynthesis of the LPS O-antigen and the LPS core. Vorholter FJ, Niehaus K, Puhler A;. Mol Genet Genomics 2001;266:79-95. (from Pfam)
sugar 3,4-ketoisomerase
sugar 3,4-ketoisomerase, such as Aneurinibacillus thermoaerophilus TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (FdtA), which mediates the isomerization of dTDP-6-deoxy-D-xylohex-4-ulose into dTDP-6-deoxy-D-xylohex-3-ulose in the biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose, a glycan chain of the S-layer
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