Protein Family Models for Protein (Select 1732743611) - Protein Family Models

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Items: 4

Select item 4173421.

zinc ribbon domain-containing protein

Proteins containing this zinc ribbon domain at the C-terminus include the RNA-guided DNA endonuclease TnpB, found as an accessory protein (that is, not required for transposition) in many IS (insertion sequence) elements.

Date:: 2024-08-14

Family Accession:: NF018933.5
Method:: HMM

Select item 3946612.

new record, indexing in progress

Family Accession:

Select item 3529573.

new record, indexing in progress

Family Accession:

Select item 511974.

RNA-guided endonuclease InsQ/TnpB family protein

RNA-guided endonuclease InsQ/TnpB family protein such as the RNA-guided endonuclease TnpB from IS200/IS605 family elements and IS607 family elements; this protein is homologous to some CRISPR-associated (Cas) proteins such as the type V CRISPR-associated protein C2c8; TnpB proteins were described as accessory proteins in IS (insertion sequence) elements, present as one of just one or two proteins encoded in the element but not necessary for transposition. The programmable RNA-guided endonuclease TnpB proteins may provide a CRISPR-like, widespread form of phage defense by RNA-guided DNA degradation.