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ferrochelatase
ferrochelatase catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway
Protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis
This family includes proteins currently designated 4.98.1.1 (protoporphyrin ferrochelatase) and 4.99.1.9 (coproporphyrin ferrochelatase). The former occurs primarily in Gram-negative bacteria and in mitochondria, the latter primarily in Gram-positive bacteria.
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