Protein Family Models for Protein (Select 1592481844) - Protein Family Models

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Links from Protein

Items: 6

Select item 4149291.

sigma factor-like helix-turn-helix DNA-binding protein

Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif [1]. Due to the way Pfam works, the threshold has been set artificially high to prevent overlaps with other helix-turn-helix families. Therefore there are many false negatives. [1]. 11931761. Structure of the bacterial RNA polymerase promoter specificity. sigma subunit.. Campbell EA, Muzzin O, Chlenov M, Sun JL, Olson CA, Weinman O,. Trester-Zedlitz ML, Darst SA;. Mol Cell 2002;9:527-539. (from Pfam)

GO Terms:

Molecular Function:: DNA-binding transcription factor activity (GO:0003700)

Biological Process:: DNA-templated transcription initiation (GO:0006352)

Biological Process:: regulation of DNA-templated transcription (GO:0006355)

Date:: 2024-08-14

Family Accession:: NF016432.5
Method:: HMM

Select item 4146872.

sugar-binding domain-containing protein

This probable domain is found in bacterial transcriptional regulators such as DeoR and SorC. These proteins have an amino-terminal helix-turn-helix Pfam:PF00325 that binds to DNA. This domain is probably the ligand regulator binding region. SorC is regulated by sorbose and other members of this family are likely to be regulated by other sugar substrates. (from Pfam)

GO Terms:

Molecular Function:: carbohydrate binding (GO:0030246)

Date:: 2024-08-14

Family Accession:: NF016114.5
Method:: HMM

Select item 3942173.

new record, indexing in progress

Family Accession:

Select item 3576144.

new record, indexing in progress

Family Accession:

Select item 3499215.

new record, indexing in progress

Family Accession:

Select item 857896.

sugar-binding transcriptional regulator

sugar-binding transcriptional regulator similar to Priestia megaterium central glycolytic genes regulator, in the absence of glucose, which represses the transcription of the gapA operon that encodes five key glycolytic enzymes