Protein Family Models for Protein (Select 1583841971) - Protein Family Models

Select item 4271171.

Bacterial DNA polymerase III alpha subunit finger domain

Date:: 2024-08-14

Family Accession:: NF036968.5
Method:: HMM

Select item 4244452.

The HHH domain is a short DNA-binding domain [1]. [1]. 8692686. The helix-hairpin-helix DNA-binding motif: a structural basis. for non-sequence-specific recognition of DNA.. Doherty AJ, Serpell LC, Ponting CP;. Nucleic Acids Res 1996;24:2488-2497. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF025930.5
Method:: HMM

Select item 4173003.

Bacterial DNA polymerase III alpha NTPase domain

GO Terms:

Biological Process:: DNA replication (GO:0006260)

Molecular Function:: 3'-5' exonuclease activity (GO:0008408)

Date:: 2024-08-14

Family Accession:: NF019353.5
Method:: HMM

Select item 4129474.

PHP domain-containing protein

The PHP (Polymerase and Histidinol Phosphatase) domain is a putative phosphoesterase domain. [1]. 9685491. Phosphoesterase domains associated with DNA polymerases of. diverse origins.. Aravind L, Koonin EV;. Nucleic Acids Res 1998;26:3746-3752. (from Pfam)

GO Terms:

Molecular Function:: catalytic activity (GO:0003824)

Date:: 2024-08-14

Family Accession:: NF014826.5
Method:: HMM

Select item 4121605.

OB-fold nucleic acid binding domain-containing protein

This family contains OB-fold domains that bind to nucleic acids [4]. The family includes the anti-codon binding domain of lysyl, aspartyl, and asparaginyl -tRNA synthetases (See Pfam:PF00152). Aminoacyl-tRNA synthetases catalyse the addition of an amino acid to the appropriate tRNA molecule EC:6.1.1.-. This family also includes part of RecG helicase involved in DNA repair. Replication factor A is a hetero-trimeric complex, that contains a subunit in this family [2,3]. This domain is also found at the C-terminus of bacterial DNA polymerase III alpha chain. [1]. 2047877. Class II aminoacyl transfer RNA synthetases: crystal structure. of yeast aspartyl-tRNA synthetase complexed with tRNA(Asp).. Ruff M, Krishnaswamy S, Boeglin M, Poterszman A, Mitschler A,. Podjarny A, Rees B, Thierry JC, Moras D;. Science 1991;252:1682-1689.. [2]. 7760808. Rpa4, a homolog of the 34-kilodalton subunit of the replication. protein A complex.. Keshav KF, Chen C, Dutta A;. Mol Cell Biol 1995;15:3119-3128.. [3]. 8990123. Structure of the single-stranded-DNA-binding domain of. replication protein A bound to DNA.. Bochkarev A, Pfuetzner RA, Edwards AM, Frappier L;. Nature 1997;385:176-181.. [4]. 10829230. Protein fold recognition using sequence profiles and its. application in structural genomics.. Koonin EV, Wolf YI, Aravind L;. Adv Protein Chem 2000;54:245-275. (from Pfam)

GO Terms:

Molecular Function:: nucleic acid binding (GO:0003676)

Date:: 2024-08-14

Family Accession:: NF013499.5
Method:: HMM

Select item 4042016.