Protein Family Models

This is a family of phosphatidylserine decarboxylases, EC:4.1.1.65. These enzymes catalyse the reaction: Phosphatidyl-L-serine <=> phosphatidylethanolamine + CO2. Phosphatidylserine decarboxylase plays a central role in the biosynthesis of aminophospholipids by converting phosphatidylserine to phosphatidylethanolamine [2]. [1]. 9422599. Cloning, sequencing, and disruption of the Bacillus subtilis psd gene coding for phosphatidylserine decarboxylase. Matsumoto K, Okada M, Horikoshi Y, Matsuzaki H, Kishi T, Itaya M, Shibuya I;. J Bacteriol 1998;180:100-106. [2]. 7890740. Phosphatidylserine decarboxylase 2 of Saccharomyces cerevisiae. Cloning and mapping of the gene, heterologous expression, and creation of the null allele. Trotter PJ, Pedretti J, Yates R, Voelker DR;. J Biol Chem 1995;270:6071-6080. (from Pfam)

Date:

2024-10-16

phosphatidylserine decarboxylase; the proenzyme is cleaved into alpha and beta subunits to form the mature enzyme that catalyzes the decarboxylaton of phospatidyl-L-serine to phosphatidylethanolamine

Date:

2015-12-21

Date:

2021-09-20