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Hydrogenase formation hypA family
HypD is involved in hydrogenase formation. It contains many possible metal binding residues, which may bind to nickel. Transposon Tn5 insertions into hypD resulted in R. leguminosarum mutants that lacked any hydrogenase activity in symbiosis with peas [1]. [1]. 8326860. Molecular analysis of a microaerobically induced operon required for hydrogenase synthesis in Rhizobium leguminosarum biovar viciae. Rey L, Murillo J, Hernando Y, Hidalgo E, Cabrera E, Imperial J, Ruiz-Argueso T;. Mol Microbiol 1993;8:471-481. (from Pfam)
HypD family hydrogenase formation protein
HypD family hydrogenase formation protein similar to hydrogenase formation protein HypD that is involved in the maturation of [NiFe] hydrogenases
hydrogenase formation protein HypD
HypD is involved in the hyp operon which is needed for the activity of the three hydrogenase isoenzymes in Escherichia coli. HypD is one of the genes needed for formation of these enzymes. This protein has been found in gram-negative and gram-positive bacteria and Archaea.
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