Protein Family Models for Protein (Select 1242933611) - Protein Family Models

Select item 4226601.

GO Terms:

Molecular Function:: ATP hydrolysis activity (GO:0016887)

Date:: 2024-08-14

Family Accession:: NF024793.5
Method:: HMM

Select item 4179852.

Protein phosphorylation, which plays a key role in most cellular activities, is a reversible process mediated by protein kinases and phosphoprotein phosphatases. Protein kinases catalyse the transfer of the gamma phosphate from nucleotide triphosphates (often ATP) to one or more amino acid residues in a protein substrate side chain, resulting in a conformational change affecting protein function. Phosphoprotein phosphatases catalyse the reverse process. Protein kinases fall into three broad classes, characterised with respect to substrate specificity [1]; Serine/threonine-protein kinases, tyrosine-protein kinases, and dual specificity protein kinases (e.g. MEK - phosphorylates both Thr and Tyr on target proteins). This entry represents the catalytic domain found in a number of serine/threonine- and tyrosine-protein kinases. It does not include the catalytic domain of dual specificity kinases. [1]. 3291115. The protein kinase family: conserved features and deduced. phylogeny of the catalytic domains.. Hanks SK, Quinn AM, Hunter T;. Science. 1988;241:42-52.. [2]. 1956325. Protein kinase catalytic domain sequence database:. identification of conserved features of primary structure and. classification of family members.. Hanks SK, Quinn AM;. Methods Enzymol 1991;200:38-62.. [3]. 7768349. Protein kinases 6. The eukaryotic protein kinase superfamily:. kinase (catalytic) domain structure and classification.. Hanks SK, Hunter T;. FASEB J 1995;9:576-596.. [4]. 9020587. The protein kinases of budding yeast: six score and more.. Hunter T, Plowman GD;. Trends Biochem Sci 1997;22:18-22. (from Pfam)

GO Terms:

Molecular Function:: protein kinase activity (GO:0004672)

Biological Process:: protein phosphorylation (GO:0006468)

Date:: 2024-08-14

Family Accession:: NF019334.5
Method:: HMM

Select item 4118173.

LuxR C-terminal-related transcriptional regulator

GO Terms:

Biological Process:: regulation of DNA-templated transcription (GO:0006355)

Date:: 2024-08-14

Family Accession:: NF012422.5
Method:: HMM

Select item 4117264.

NB-ARC domain-containing protein

GO Terms:

Molecular Function:: ADP binding (GO:0043531)

Date:: 2024-08-14

Family Accession:: NF013124.5
Method:: HMM

Select item 4108705.

Protein kinase domain

GO Terms:

Molecular Function:: protein kinase activity (GO:0004672)

Molecular Function:: ATP binding (GO:0005524)

Biological Process:: protein phosphorylation (GO:0006468)

Date:: 2024-08-14

Family Accession:: NF012298.5
Method:: HMM

Select item 3991876.