Protein Family Models

This family of TraC proteins is conserved in Proteobacteria. TraC is a cytoplasmic, peripheral membrane protein and is one of the proteins encoded by the F transfer region of the conjugative plasmid that is required for the assembly of F pilin into the mature F pilus structure. F pili are filamentous appendages that help establish the physical contact between donor and recipient cells involved in the conjugation process [1]. [1]. 1350587. Localization of TraC, a protein involved in assembly of the F conjugative pilus. Schandel KA, Muller MM, Webster RE;. J Bacteriol. 1992;174:3800-3806. (from Pfam)

Date:

2024-10-16

conjugative transfer ATPase similar to TraC, one of the proteins encoded by the transfer (tra) region of the F pilus assembly Type-IV secretion system for plasmid transfer; is required for the assembly of mature F-pilin subunits into extended F pili

Date:

2018-04-16

Members of this protein family are predicted ATP-binding proteins apparently associated with DNA conjugal transfer. Members are found both in plasmids and in bacterial chromosomal regions that appear to derive from integrative elements such as conjugative transposons. More distant homologs, outside the scope of this family, include type IV secretion/conjugal transfer proteins such as TraC, VirB4 and TrsE. The granularity of this protein family definition is chosen so as to represent one distinctive clade and act as a marker through which to define and recognize the class of mobile element it serves.

Date:

2024-08-07