Protein Family Models for Protein (Select 1159822726) - Protein Family Models

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Items: 4

Select item 4125141.

S49 family peptidase

GO Terms:

Biological Process:: proteolysis (GO:0006508)

Molecular Function:: peptidase activity (GO:0008233)

Date:: 2024-08-14

Family Accession:: NF013506.5
Method:: HMM

Select item 3902722.

new record, indexing in progress

Family Accession:

Select item 3478123.

new record, indexing in progress

Family Accession:

Select item 224354.

signal peptide peptidase SppA

The related but duplicated, double-length protein SppA (protease IV) of E. coli was shown experimentally to degrade signal peptides as are released by protein processing and secretion. This protein shows stronger homology to the C-terminal region of SppA than to the N-terminal domain or to the related putative protease SuhB. The member of this family from Bacillus subtilis was shown to have properties consistent with a role in degrading signal peptides after cleavage from precursor proteins, although it was not demonstrated conclusively.