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Items: 5

1.
new record, indexing in progress
Family Accession:
2.
new record, indexing in progress
Family Accession:
3.

cell envelope integrity protein TolA

cell envelope integrity protein TolA is part of the Tol-Pal system that plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity

Date:
2019-05-01
Family Accession:
11484310
Method:
Sparcle
4.

cell envelope integrity protein TolA

TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB.

Gene:
tolA
GO Terms:
Molecular Function:
transporter activity (GO:0005215)
Biological Process:
transport (GO:0006810)
Cellular Component:
periplasmic side of plasma membrane (GO:0098567)
Date:
2022-10-11
Family Accession:
TIGR02794.1
Method:
HMM
5.

cell envelope integrity protein TolA

Inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins

Gene:
tolA
GO Terms:
Cellular Component:
membrane (GO:0016020)
Molecular Function:
toxin transmembrane transporter activity (GO:0019534)
Biological Process:
bacteriocin transport (GO:0043213)
Date:
2022-10-11
Family Accession:
NF007065.0
Method:
HMM
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