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lipid A ABC transporter ATP-binding protein/permease MsbA
lipid A ABC transporter ATP-binding protein/permease MsbA functions as a homodimeric lipid flippase that exports lipid A from the inner to the outer leaflet of the plasma membrane and contains the transmembrane permease domain fused to the ATP-binding domain
lipid A export permease/ATP-binding protein MsbA
This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes.
Involved in the transport of lipid A across the inner membrane
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