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maleylacetoacetate isomerase
Maleylacetoacetate isomerase is an enzyme of tyrosine and phenylalanine catabolism. It requires glutathione and belongs by homology to the zeta family of glutathione S-transferases. The enzyme (EC 5.2.1.2) is described as active also on maleylpyruvate, and the example from a Ralstonia sp. catabolic plasmid is described as a maleylpyruvate isomerase involved in gentisate catabolism.
maleylacetoacetate isomerase is a bifunctional enzyme that shows maleylacetoacetate isomerase activity using glutathione as a cofactor and minimal glutathione-conjugating activity
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