Protein Family Models for Gene (Select 69901277) - Protein Family Models

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Links from Gene

Items: 6

Select item 4069191.

new record, indexing in progress

Family Accession:

Select item 3889602.

new record, indexing in progress

Family Accession:

Select item 3475553.

new record, indexing in progress

Family Accession:

Select item 2962244.

quorum-sensing system transcriptional regulator Rgg2

Gene:: rgg2

Date:: 2020-12-17

Family Accession:: NBR013582
Method:: BlastRule

Select item 1427865.

transcriptional activator, Rgg/GadR/MutR family, C-terminal domain

This HMM describes the whole, except for a 60 residue N-terminal helix-turn-helix DNA-binding domain (PFAM PF01381) of the family of proteins related to the transcriptional regulator Rgg, also called RopB. Rgg is required for secretion of several proteins, including a cysteine proteinase associated with virulence. GadR (GP|2352485) is a positive regulator of a glutamate-dependent acid resistance mechanism. MutR is a transcriptional activator for mutacin biosynthesis genes in Streptococcus mutans. This family appears restricted to the low-GC Gram-positive bacteria, including at least eight members in Lactococcus lactis.

GO Terms: