Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
PDB: 1I9Q_A
Identical Proteins FASTA Graphics
LOCUS 1I9Q_A 259 aa linear PRI 07-FEB-2024 DEFINITION Chain A, CARBONIC ANHYDRASE II. ACCESSION 1I9Q_A VERSION 1I9Q_A DBSOURCE pdb: molecule 1I9Q, chain A, release Feb 7, 2024; deposition: Mar 20, 2001; class: LYASE; source: Mmdb_id: 15860, Pdb_id 1: 1I9Q; Exp. method: X-ray Diffraction. KEYWORDS . SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (residues 1 to 259) AUTHORS Kim,C.Y., Chandra,P.P., Jain,A. and Christianson,D.W. TITLE Fluoroaromatic-fluoroaromatic interactions between inhibitors bound in the crystal lattice of human carbonic anhydrase II JOURNAL J Am Chem Soc 123 (39), 9620-9627 (2001) PUBMED 11572683 REFERENCE 2 (residues 1 to 259) AUTHORS Kim,C.-Y., Chandra,P.P., Jain,A. and Christianson,D.W. TITLE Direct Submission JOURNAL Submitted (20-MAR-2001) COMMENT CARBONIC ANHYDRASE II (F131V) COMPLEXED WITH 4-(AMINOSULFONYL)-N-[(3,4,5-TRIFLUOROPHENYL)METHYL]-BENZAMIDE. FEATURES Location/Qualifiers source 1..259 /organism="Homo sapiens" /db_xref="taxon:9606" Region 1..258 /region_name="alpha_CA_I_II_III_XIII" /note="Carbonic anhydrase alpha, isozymes I, II, and III and XIII. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on...; cd03119" /db_xref="CDD:239393" SecStr 29..33 /sec_str_type="sheet" /note="strand 1" SecStr 37..40 /sec_str_type="sheet" /note="strand 2" SecStr 45..50 /sec_str_type="sheet" /note="strand 3" SecStr 54..62 /sec_str_type="sheet" /note="strand 4" Site order(63,91,93,95,105,118,197) /site_type="active" /db_xref="CDD:239393" SecStr 63..70 /sec_str_type="sheet" /note="strand 5" SecStr 76..81 /sec_str_type="sheet" /note="strand 6" SecStr 86..91 /sec_str_type="sheet" /note="strand 7" SecStr 92..98 /sec_str_type="sheet" /note="strand 8" Het join(bond(93),bond(95),bond(118)) /heterogen="(ZN,2055)" Site order(93,95,118) /site_type="other" /note="zinc binding site [ion binding]" /db_xref="CDD:239393" SecStr 105..109 /sec_str_type="sheet" /note="strand 9" SecStr 114..123 /sec_str_type="sheet" /note="strand 10" SecStr 138..148 /sec_str_type="sheet" /note="strand 11" SecStr 169..176 /sec_str_type="sheet" /note="strand 12" SecStr 188..194 /sec_str_type="sheet" /note="strand 13" SecStr 204..211 /sec_str_type="sheet" /note="strand 14" SecStr 213..216 /sec_str_type="sheet" /note="strand 15" SecStr 219..226 /sec_str_type="helix" /note="helix 1" SecStr 240..243 /sec_str_type="sheet" /note="strand 16" SecStr 254..258 /sec_str_type="sheet" /note="strand 17" ORIGIN 1 shhwgygkhn gpehwhkdfp iakgerqspv didthtakyd pslkplsvsy dqatslriln 61 nghafnvefd dsqdkavlkg gpldgtyrli qfhfhwgsld gqgsehtvdk kkyaaelhlv 121 hwntkygdvg kavqqpdgla vlgiflkvgs akpglqkvvd vldsiktkgk sadftnfdpr 181 gllpesldyw typgslttpp llecvtwivl kepisvsseq vlkfrklnfn gegepeelmv 241 dnwrpaqplk nrqikasfk //
Whole sequence Selected region from: to:
Conserved Domains
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on