RecName: Full=COP9 signalosome complex subunit 2; Short=SGN2; Short=Si - Protein

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Suramin and NF449 are IP5K inhibitors that disrupt inositol hexakisphosphate-mediated regulation of cullin-RING ligase and sensitize cancer cells to MLN4924/pevonedistat. [J Biol Chem. 2020]
Suramin and NF449 are IP5K inhibitors that disrupt inositol hexakisphosphate-mediated regulation of cullin-RING ligase and sensitize cancer cells to MLN4924/pevonedistat.
Zhang X, Shi S, Su Y, Yang X, He S, Yang X, Wu J, Zhang J, Rao F. J Biol Chem. 2020 Jul 24; 295(30):10281-10292. Epub 2020 Jun 3.
Exercise training reverses cancer-induced oxidative stress and decrease in muscle COPS2/TRIP15/ALIEN. [Mol Metab. 2020]
Exercise training reverses cancer-induced oxidative stress and decrease in muscle COPS2/TRIP15/ALIEN.
Alves CRR, Neves WD, de Almeida NR, Eichelberger EJ, Jannig PR, Voltarelli VA, Tobias GC, Bechara LRG, de Paula Faria D, Alves MJN, et al. Mol Metab. 2020 Sep; 39:101012. Epub 2020 May 11.
Cops2 promotes pluripotency maintenance by Stabilizing Nanog Protein and Repressing Transcription. [Sci Rep. 2016]
Cops2 promotes pluripotency maintenance by Stabilizing Nanog Protein and Repressing Transcription.
Zhang W, Ni P, Mou C, Zhang Y, Guo H, Zhao T, Loh YH, Chen L. Sci Rep. 2016 May 26; 6:26804. Epub 2016 May 26.

RefSeq protein isoforms
See 2 reference sequence protein isoforms for the COPS2 gene.

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P61201 [Domain Mapping of Disease Mut...]
P61201
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
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reagents [ExactAntigen/Labome]
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ExactAntigen/Labome

RecName: Full=COP9 signalosome complex subunit 2; Short=SGN2; Short=Signalosome ...
RecName: Full=COP9 signalosome complex subunit 2; Short=SGN2; Short=Signalosome subunit 2; AltName: Full=Alien homolog; AltName: Full=JAB1-containing signalosome subunit 2; AltName: Full=Thyroid receptor-interacting protein 15; Short=TR-interacting protein 15; Short=TRIP-15
gi|47117681|sp|P61201.1|CSN2_HUMAN

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