RecName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2; - Protein

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The Rho family GEF FARP2 is activated by aPKCι to control tight junction formation and polarity. [J Cell Sci. 2019]
The Rho family GEF FARP2 is activated by aPKCι to control tight junction formation and polarity.
Elbediwy A, Zhang Y, Cobbaut M, Riou P, Tan RS, Roberts SK, Tynan C, George R, Kjaer S, Martin-Fernandez ML, et al. J Cell Sci. 2019 Apr 25; 132(8). Epub 2019 Apr 25.
Src kinase regulates the activation of a novel FGD-1-related Cdc42 guanine nucleotide exchange factor in the signaling pathway from the endothelin A receptor to JNK. [J Biol Chem. 2003]
Src kinase regulates the activation of a novel FGD-1-related Cdc42 guanine nucleotide exchange factor in the signaling pathway from the endothelin A receptor to JNK.
Miyamoto Y, Yamauchi J, Itoh H. J Biol Chem. 2003 Aug 8; 278(32):29890-900. Epub 2003 May 27.
Inherited genetic susceptibility to monoclonal B-cell lymphocytosis. [Blood. 2010]
Inherited genetic susceptibility to monoclonal B-cell lymphocytosis.
Crowther-Swanepoel D, Corre T, Lloyd A, Gaidano G, Olver B, Bennett FL, Doughty C, Toniolo D, Caligaris-Cappio F, Ghia P, et al. Blood. 2010 Dec 23; 116(26):5957-60. Epub 2010 Sep 20.

RefSeq protein isoforms
See 21 reference sequence protein isoforms for the FARP2 gene.

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O94887 [Domain Mapping of Disease Mut...]
O94887
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
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RecName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2; AltName: ...
RecName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2; AltName: Full=FERM domain-including RhoGEF; Short=FIR; AltName: Full=FERM, RhoGEF and pleckstrin domain-containing protein 2; AltName: Full=Pleckstrin homology domain-containing family C member 3; Short=PH domain-containing family C member 3
gi|93204574|sp|O94887.3|FARP2_HUMAN

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