RecName: Full=Cytochrome c oxidase assembly factor 8; Short=COA8; AltN - Protein

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Knockdown of APOPT1/COA8 Causes Cytochrome c Oxidase Deficiency, Neuromuscular Impairment, and Reduced Resistance to Oxidative Stress in Drosophila melanogaster. [Front Physiol. 2019]
Knockdown of APOPT1/COA8 Causes Cytochrome c Oxidase Deficiency, Neuromuscular Impairment, and Reduced Resistance to Oxidative Stress in Drosophila melanogaster.
Brischigliaro M, Corrà S, Tregnago C, Fernandez-Vizarra E, Zeviani M, Costa R, De Pittà C. Front Physiol. 2019; 10:1143. Epub 2019 Sep 6.
Mutations in APOPT1, encoding a mitochondrial protein, cause cavitating leukoencephalopathy with cytochrome c oxidase deficiency. [Am J Hum Genet. 2014]
Mutations in APOPT1, encoding a mitochondrial protein, cause cavitating leukoencephalopathy with cytochrome c oxidase deficiency.
Melchionda L, Haack TB, Hardy S, Abbink TE, Fernandez-Vizarra E, Lamantea E, Marchet S, Morandi L, Moggio M, Carrozzo R, et al. Am J Hum Genet. 2014 Sep 4; 95(3):315-25. Epub 2014 Aug 28.
APOPT1/COA8 assists COX assembly and is oppositely regulated by UPS and ROS. [EMBO Mol Med. 2019]
APOPT1/COA8 assists COX assembly and is oppositely regulated by UPS and ROS.
Signes A, Cerutti R, Dickson AS, Benincá C, Hinchy EC, Ghezzi D, Carrozzo R, Bertini E, Murphy MP, Nathan JA, et al. EMBO Mol Med. 2019 Jan; 11(1).

RefSeq genomic sequence
See the genomic reference sequence for the COA8 gene (NG_041786.1).
RefSeq protein isoforms
See 3 reference sequence protein isoforms for the COA8 gene.

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Q96IL0 [Domain Mapping of Disease Mut...]
Q96IL0
Domain Mapping of Disease Mutations
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reagents [ExactAntigen/Labome]
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ExactAntigen/Labome

RecName: Full=Cytochrome c oxidase assembly factor 8; Short=COA8; AltName: Full=...
RecName: Full=Cytochrome c oxidase assembly factor 8; Short=COA8; AltName: Full=Apoptogenic protein 1, mitochondrial; Short=APOP-1; Flags: Precursor
gi|363548522|sp|Q96IL0.3|COA8_HUMAN

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